Here are a couple from the hyperlipidemics since we skipped them last meeting.
Bile Acid sequestrants
(cholestipol, cholestyramine, colesevelam)
- on the USMLE, we're going to be given these drugs and we'll have to know if they are bile acid sequestrants.
mn
- the drugs start with 'chol' meaning they work in the colon
Once you know their mode of action, you can figure out what happens to the VLDL, LDL, & HDL.
Ezetimibe
- blocks the cholesterol transporter in the GI
mn
- I just think of it acting according to the EZest mechanism out there. The drug doesn't bother entering the blood, hepatocytes, or endothelial cells; it just stays in the GI and does its work there.
These are all the mnemonics I have for hyperlipidemics. If you guys have anything else, please post!
Antibacterials
- from First Aid
B lactamase resistant (2nd generation penicillins)
- Kaplan is great for this. They give you an understanding of why these drugs were created in the first place....to combat those microbes producing B lactamases!
mn (for the main bug it's used for)
- naf is for Staph (not MRSA though)
Tuesday, October 26, 2010
Saturday, October 23, 2010
Cephalosporins p.192
Cephalosporins (kaplan pharmacology book p.192)
Mechanism;
Similar to Penicillin but Cephalosporins are beta-lactamase resistant. Each generation (1st/2nd/3rd) has different effectivity for each kind of bacteria.
.
Gram (-); 3rd > 2nd > 1st
Pneumococcus; 1st/3rd > 2nd
Gram (+); 1st > 2nd > 3rd
.
Mneumonics; Clinical microbio made easy p.158-160
(To know names of drugs for each generation)
1st generation;
"You must get a PH.D. in PHarmacology"
cef + ph = first generation.
cephalothin
cephradine
cephalexin
2nd generation;
"The FAMily is gathered, some wearing FUR coats, and yor FOXy cousin is drinking TEA."
cefamandole
cefaclor
cefuroxime
3rd generation;
"TRI for third."
ceftriaxone
ceftrazidime
cefotaxime
ceftizoxime
ceftibuten
4th generation;
cefepime
Mechanism;
Similar to Penicillin but Cephalosporins are beta-lactamase resistant. Each generation (1st/2nd/3rd) has different effectivity for each kind of bacteria.
.
Gram (-); 3rd > 2nd > 1st
Pneumococcus; 1st/3rd > 2nd
Gram (+); 1st > 2nd > 3rd
.
Mneumonics; Clinical microbio made easy p.158-160
(To know names of drugs for each generation)
1st generation;
"You must get a PH.D. in PHarmacology"
cef + ph = first generation.
cephalothin
cephradine
cephalexin
2nd generation;
"The FAMily is gathered, some wearing FUR coats, and yor FOXy cousin is drinking TEA."
cefamandole
cefaclor
cefuroxime
3rd generation;
"TRI for third."
ceftriaxone
ceftrazidime
cefotaxime
ceftizoxime
ceftibuten
4th generation;
cefepime
Wednesday, October 20, 2010
Oct 20, 2010
The mnemonics for micro are great in First Aid and MMRS, so I can't really compete with their mnemonics this time.
Drugs which are bactericidal
- look at First AID
Very Finely Proficient At Cell Murder!
All the rest at bacteriostatic.
Penicillin
- this is quite obvious
- just have to keep in mind that although it can kill a broad range of bugs, it can't kill those that produce penicillinase (most notably Staph aureus)
Mechanism
- blocks cross linking in the cell wall
mn
- think of a pen blocking the transpeptidases from cross linking the wall
- a pen can be used to kill alot of bugs, but can't be used to kill a STAFF (or bundle) of bugs.
Drugs which are bactericidal
- look at First AID
Very Finely Proficient At Cell Murder!
All the rest at bacteriostatic.
Penicillin
- this is quite obvious
- just have to keep in mind that although it can kill a broad range of bugs, it can't kill those that produce penicillinase (most notably Staph aureus)
Mechanism
- blocks cross linking in the cell wall
mn
- think of a pen blocking the transpeptidases from cross linking the wall
- a pen can be used to kill alot of bugs, but can't be used to kill a STAFF (or bundle) of bugs.
Wednesday, October 13, 2010
Let's make things a bit more organized
Great fun today everyone!
Deb raised a good point about how to organize things a bit better. In order to be more effective during the meeting and to prevent people flipping through tons of notes, books, etc, we're going to do everything in the order of Kaplan, something we haven't done the last 2 meetings.
So, we learn from Kaplan, we post in the order of Kaplan, and we also meet and discuss in the order of Kaplan. But remember to use FirstAid to see what's super high yield and what to emphasize when studying!
As far as I'm concerned, WE ARE Kaplan Pharm MSIH!
So, when we start micro drugs next week, we'll go in the order of Kaplan. So, during the meeting, you can just bring the Kaplan book and any notes/mnemonics you have.
Deb raised a good point about how to organize things a bit better. In order to be more effective during the meeting and to prevent people flipping through tons of notes, books, etc, we're going to do everything in the order of Kaplan, something we haven't done the last 2 meetings.
So, we learn from Kaplan, we post in the order of Kaplan, and we also meet and discuss in the order of Kaplan. But remember to use FirstAid to see what's super high yield and what to emphasize when studying!
As far as I'm concerned, WE ARE Kaplan Pharm MSIH!
So, when we start micro drugs next week, we'll go in the order of Kaplan. So, during the meeting, you can just bring the Kaplan book and any notes/mnemonics you have.
Tuesday, October 12, 2010
Meeting tomorrow at 12:30 at fake Aroma
Alright team!
I'll bring my mnemonics tomorrow!
So just bring your lunch and bring your mnemonics or any helpful tips you have to remember these cardio drugs. These are really high yield, so we need effective ways of remembering these long term, and also some of their special side effects.
I also have some mnemonics for the foundational SANS drugs, but we can go over them another time or you can just ask me one on one anytime.
PS: I haven't covered antihyperlipidemics well, so I have nothing in store for that section.
I'll bring my mnemonics tomorrow!
So just bring your lunch and bring your mnemonics or any helpful tips you have to remember these cardio drugs. These are really high yield, so we need effective ways of remembering these long term, and also some of their special side effects.
I also have some mnemonics for the foundational SANS drugs, but we can go over them another time or you can just ask me one on one anytime.
PS: I haven't covered antihyperlipidemics well, so I have nothing in store for that section.
Monday, October 11, 2010
Antihypertensive: Vasodilators (pg. 272 of First Aid)
Hydralazine, Minoxidil, Nifedipine, Verapamil, Nitroprusside, Diazoxide -->
He May Never Vasodilate Nor Decrease hypertension
Meeting on Wed 12:30 (just after ICCU)
Hey Pharmonics team!
Looks like things are a bit stalled on the blog, but understandably so since it's been so busy lately. Try to read chapters 1-5, and 7 in Kaplan before the meeting and then we'll hit the drugs one by one in First Aid.
Kaplan covers a few drugs which are not covered in First Aid. I don't think they're important, so we won't go over them.
Bring all the mnemonics you came up with during your studying. I'm having major trouble thinking of some, but I'll bring what I got!
We won't go over the foundational SANS stuff unless you guys really want to. We got to keep rolling here and move forward, so if you haven't looked at that stuff, I highly recommend doing so when you find some spare time. So after the cardio drugs, we'll start looking back at the Micro drugs...a good way to start off respi !
You know what they say, the best way to learn material is to teach it ! And that's what the meetings are for. Also, it's great to set a deadline. So let's all have some familiarity with all the cardio drugs by Wednesday!
Keep up the great work everyone!!!
Looks like things are a bit stalled on the blog, but understandably so since it's been so busy lately. Try to read chapters 1-5, and 7 in Kaplan before the meeting and then we'll hit the drugs one by one in First Aid.
Kaplan covers a few drugs which are not covered in First Aid. I don't think they're important, so we won't go over them.
Bring all the mnemonics you came up with during your studying. I'm having major trouble thinking of some, but I'll bring what I got!
We won't go over the foundational SANS stuff unless you guys really want to. We got to keep rolling here and move forward, so if you haven't looked at that stuff, I highly recommend doing so when you find some spare time. So after the cardio drugs, we'll start looking back at the Micro drugs...a good way to start off respi !
You know what they say, the best way to learn material is to teach it ! And that's what the meetings are for. Also, it's great to set a deadline. So let's all have some familiarity with all the cardio drugs by Wednesday!
Keep up the great work everyone!!!
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