Sunday, October 3, 2010

As I have mentioned to a few of you, I think it's actually really important to have a good foundation of SANS drugs before cardio drugs. We can do them 4 at a time to just breeze through before plunge into cardio would be my vote. Here it is:

*phenylephrine

Mech: alpha 1 agonist
rx: decongestion, mydriasis without cycloplegia (although M antagonists are preferred, what are they again?)

mn: I know lindsey already covered this drug, but I have a really good one. We can use both. "Fan the norepinephrine into your nose to treat decongestion"

1)Methoxamine

Mech: alpha 1 agonist
rx: used in IV form to elicit reflex bradycardia from vagal reflex actually to treat paroxysmal atrial tachycardia (sudden atrial tachycardia basically very acute, not life threatening)

mn: methoxamine is a norepinephrine mimic drug. If you remember how to make a norepi from tyrosine, then you know you have to throw things out to make a norepi leaving the amine group (hence dopamine). So, "me throw things out, leaving only an amine to make a norepi"

2, 3) salmeterol, albuterol, metaproterenol, terbutaline

Mech: beta 2 agonist
rx: ashma

mn: just to cover them together. "a salmon and an abalone (google image) are swimming to open your lungs again"
metaproterenol, "remember isoproterenol? well, this one is selective for beta2 only, meta means beyond, or after in greek, so beyond your beta 1 in the heart, you work on beta2 on your lungs"
terbutaline---imagine a singer saying this on stage: "a tribute to lin (Asian girl here), who is my love, the breath of my life".

4) Ritodrine

mech: beta 2 agonist
rx: premature labor, cause uterine muscle relaxation

mn: Rita from mexico got an unwanted pregnancy. She doesn't have money so she tries to pop her own water to make the child come out sooner. You should tell her, "woo there! if you DRAIN (drine) your water, Rita, you will have a premature labor. DON'T DO THAT!"

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