Cephalosporins (kaplan pharmacology book p.192)
Mechanism;
Similar to Penicillin but Cephalosporins are beta-lactamase resistant. Each generation (1st/2nd/3rd) has different effectivity for each kind of bacteria.
.
Gram (-); 3rd > 2nd > 1st
Pneumococcus; 1st/3rd > 2nd
Gram (+); 1st > 2nd > 3rd
.
Mneumonics; Clinical microbio made easy p.158-160
(To know names of drugs for each generation)
1st generation;
"You must get a PH.D. in PHarmacology"
cef + ph = first generation.
cephalothin
cephradine
cephalexin
2nd generation;
"The FAMily is gathered, some wearing FUR coats, and yor FOXy cousin is drinking TEA."
cefamandole
cefaclor
cefuroxime
3rd generation;
"TRI for third."
ceftriaxone
ceftrazidime
cefotaxime
ceftizoxime
ceftibuten
4th generation;
cefepime
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